Users Folder Missing

I've got a laptop where there were errors when trying to log in, I removed the hard drive and connected it to desktop and found the entire Users folder was missing!

Although in the C:/ there is a Users file with 0kb size which I'm sure is the Users folder but some how changed to a file by corruption or virus?

(Pic attached)

Have done chkdsk /r but no change.

Can anyone help?

Thanks

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