Windows cannot access the specified device, path or file.

I keep getting the error 'Windows cannot access the specified device, path or file. You may not have the appropriate permissions to access the item.' whenever I try to run as adminstratorr or run something that requires adminstrator access. It only started happening a few weeks ago, I'm not sure what the cause is. I'm on an adminstrator's account?

via Bleeping Computer Last 20 Posts http://www.bleepingcomputer.com/forums/t/509451/windows-cannot-access-the-specified-device-path-or-file/